Administration of testosterone results in reversible deterioration in Kennedy’s disease Click Here

A Comprehensive Endocrine Description of Kennedy's Disease Revealing Androgen Insensitivity Linked to CAG Repeat Length

Whole-body Gene Therapy Developed for Muscular Dystrophy

"Proof of principle" that delivering new genes to all muscles is possible

A Comprehensive Endocrine Description of Kennedy's Disease Revealing Androgen Insensitivity Linked to CAG Repeat Length

VEGF Deficiency Implicated in Second Disease

Risks and Benefits of DNA testing for Neurological disorders

Gene Regulation by Nuclear Receptors A group is focusing on the mechanism of gene regulation by the human androgen receptor (AR).

An on-line exhibit on genetics research, sponsored by the Office of NIH History, is now available on the World Wide Web. The exhibit answers important questions about genetics research and features cartoons to increase children's interest in genetics.  A physical version of the exhibit is also on display at the NIH Clinical Center.

Scientists Search for Drugs to help Kennedy's Disease At the 55th Annual meeting of the American Academy of Neurology, scientists reported  that they've scored multiple "hits" in a screen for drugs that might be useful against Kennedy's disease.

DNA Sticky Tape Treatment Scientists believe they can stop certain genetic diseases by correcting DNA mutations.

New Gene Therapy Fights Frailty. New research suggests muscle wasting process may be halted. (Brief Article)

Bone Marrow Cells can Build New Muscle. Finding suggests novel avenues to explore in treating muscular dystrophies and other muscle-wasting diseases.

Dying to find Muscle Stem Cells. Research into the use of muscle stem cell transplantation in order to combat muscle diseases. (Brief Article)

Multiple SBMA Abstracts and Full Text Research Articles   Human Molecular Genetics - Oxford Journals

SBMA Individuals May Have a Low-Risk of Prostate Cancer   Genetic alterations of Androgen Receptor Gene

Lateral Corticospinal Tract and Spinal Ventral Horn in X-Linked SBMA    Abstract by Terao, Sobue, Hashizume, Tanaka & Mitsuma

Mutation Properties of SBMA Disease Alleles    Abstract by Grewel, Leeflang, Zhang & Arnheim

Kennedy's Disease Genetic Diagnosis    Abstract by Bing-Wen Soong

Motor Neuronpathies    Comparison of SBMA and other motor neuron diseases 

Dr. Kenneth H. Fischbeck, M.D., and Staff    Chief of the Neurogenetics Branch which investigates the causes of neurological diseases, including SBMA

Ask the Experts    Questions and Answers Posted About SBMA by the Muscular Dystrophy Association

Facts About Spinal Muscular Atrophy (Including SBMA)    Muscular Dystrophy Association answers basic questions regarding SMA and SBMA

Researching Protein Clumping and the Cause of Cell Death    Dr. Diane Merry, Ph.D., leads a team of researchers. (Scroll down to "Studies Suggest New Directions in SBMA.)

Protein Clumps Clue to Ataxias, SBMA     Researchers believe they have reached a turning point in which they can now begin developing evaluations for drugs (scroll down for article).

Kennedy's Symposium 2000    Families of SMA Conference June, 2000.  Researchers, Doctors, SBMA individuals convene for an update on medical research.

Kennedy's Symposium 2001    Families of SMA Conference June, 2001.  Dr. Kenneth Fischbeck and Dr. Diane Merry discuss SBMA research advancements and have a question & answer session with Kennedy's individuals and family members.

Clinical Trial Currently Being Conducted  Year 1992, Dr. Jerry Mendell of Ohio State University is evaluating the effects of androgen suppression with leuprolide and androgen replacement with testosterone enanthate on muscle strength in men with Kennedy's disease or other motor neuron disease.

History of SBMA Research   Descriptive timeline of SBMA discoveries - once in the link, scroll down for information.

SBMA Overview     Dr. Albert La Spada, Ph.D., summarizes SBMA including diagnosis, management, genetic counseling, molecular genetics, and resource information.