Kennedy's Disease Association

"KDA is One SUPER, Non-Profit Organization."

• Natural History of SBMA
  Descriptive timeline of SBMA discoveries - once in the link, scroll down for information.
• Researcher Seeks treatment for SBMA and Other Motor Neuron Diseases
• Stem cells 'treat muscle disease'
• Use of epidural anaesthesia for surgery in a patient with Kennedy’s disease
• Administration of testosterone results in reversible deterioration in Kennedy’s disease
• Kennedy's disease phenotype with positive genetic study for Kugelberg-Welander's disease: case report
• A Comprehensive Endocrine Description of Kennedy’s Disease Revealing Androgen Insensitivity Linked to CAG Repeat Length
• Whole-body Gene Therapy Developed for Muscular Dystrophy
  "Proof of principle" that delivering new genes to all muscles is possible
• VEGF Deficiency Implicated in Second Disease
• NINDS Kennedy's Disease Information page
• DNA testing for Disease
• The classical direct effects of nuclear receptors on gene regulation
• Human Genetics and Medical Research
  An on-line exhibit on genetics research, sponsored by the Office of NIH History, is now available on the World Wide Web. The exhibit answers important questions about genetics research and features cartoons to increase children's interest in genetics.  A physical version of the exhibit is also on display at the NIH Clinical Center.
• Spinal and Bulbar Muscular Atrophy - Clinical Features and Pathogenesis - PDF Document
• Leuprorelin Rescues Polyglutamine-Dependent Phenotypes in Transgenic Mouse model of Spinal & Bulbar Muscular Atrophy - PDF Document
  June 2003 article - research team:  Masahisa Katsuno, Hiroaki Adachi, Manabu Doyu, Makoto Minimiyama, Chen Sang, Yasushi Koboyashi, Akira Inukai and Gen Sobue, University of Nagoya
• New Clues Found to SBMA Mechanism, Treatment (MDA Article Quest)
  May/June 2003 article
• Scientists Search for Drugs to help Kennedy's Disease
  At the 55th Annual meeting of the American Academy of Neurology, scientists reported  that they've scored multiple "hits" in a screen for drugs that might be useful against Kennedy's disease.
• DNA Sticky Tape Treatment
  Scientists believe they can stop certain genetic diseases by correcting DNA mutations.
• New Gene Therapy Fights Frailty
  New research suggests muscle wasting process may be halted.
• Bone marrow cells can build new muscle
  Finding suggests novel avenues to explore in treating muscular dystrophies and other muscle-wasting diseases.
• Dyeing to find muscle stem cells
  Research into the use of muscle stem cell transplantation in order to combat muscle diseases.
• Multiple SBMA Abstracts and Full Text Research Articles
  Human Molecular Genetics
• SBMA Individuals May Have a Low-Risk of Prostate Cancer
  Genetic alterations of Androgen Receptor Gene
• Lateral Corticospinal Tract and Spinal Ventral Horn in X-Linked SBMA
  Abstract by Terao, Sobue, Hashizume, Tanaka & Mitsuma
• Mutation Properties of SBMA Disease Alleles
  Abstract by Grewel, Leeflang, Zhang & Arnheim
• Kennedy's Disease Genetic Diagnosis
  Abstract by Bing-Wen Soong
• Therapy Investigated for ALS May Find New Role in Kennedy’s Disease
• Facts About Spinal Muscular Atrophy (SMA)
• Researching Protein Clumping and the Cause of Cell Death
  Dr. Diane Merry, Ph.D., leads a team of researchers. (Scroll down to "Studies Suggest New Directions in SBMA.)
• Protein Clumps Clue to Ataxias, SBMA
• 2000 - June 10, Kennedy’s Symposium (Spinal Bulbar Muscular Atrophy –SBMA)
  Families of SMA Conference June, 2000.  Researchers, Doctors, SBMA individuals convene for an update on medical research.
• 2001 - June 21-24, Kennedy’s Symposium (Spinal Bulbar Muscular Atrophy –SBMA)
  Families of SMA Conference June, 2001.  Dr. Kenneth Fischbeck and Dr. Diane Merry discuss SBMA research advancements and have a question & answer session with Kennedy's individuals and family members.
• Clinical Trial Conducted - Old trial (2000)
  Dr. Albert La Spada, Ph.D., summarizes SBMA including diagnosis, management, genetic counseling, molecular genetics, and resource information.