Kennedy's Disease Association

A Public Benefit, Non-Profit Organization

"Back in the late 1990s, I felt alone. I had just been diagnosed with Kennedy's Disease. I came across the KDA and attended a Saturday chat. What an eye opener! There were two dozen others on the chat that were going through what I was experiencing."

Living with

Kennedy's Disease Blog

Living_with_KD_Logo_-_medium


 "I am amazed at the wonderful support that the KDA gives to the men and families affected by KD. The progress made by current research on animal models of KD and by therapeutic trials gives reason to hope that the disease that I described 40 years ago will finally be conquered."
-- William R. Kennedy, M.D.
Today
Yesterday
This Week
Last Week
This Month
Last Month
All days
117
2876
7132
20617
39816
0
2559226


44 guests
no members

Your IP:54.82.31.133

 

The Kennedy’s Disease Association has worked to educate others about this lesser-known disease and to support clinical research efforts.

read more

 

It takes an enormous amount of money to fund research…more than any of us can afford alone, but together, we are capable of great accomplishments.

read more

 

It is passed on from generation to generation in families worldwide. Males generally inherit the disease symptoms and females are the carriers.

read more

 

Kennedy’s Disease (spinal and bulbar muscular atrophy) is an adult-onset “X” linked inherited disease with symptoms usually beginning to appear between the ages of 30 and 50.

read more

Help Us Find A Cure!

nord-member-org.300x100

What-is-new

 

 
 

Home

KDA-Welcome

First-Time-Visitor  Update-Keep-Us

 


Hear Ye, Hear Ye...

Announcing the 2014 KDA Conference

Conf-registration

The 2014 Kennedy’s Disease Conference will be held in Alexandria Old Town, Virginia
November 12 – 14

kda2014conference_banner

Click the image above for more information


You are not alone because we are all family

KDA-Family-Story-Slow-1200

The KDA's mission is to inform, support, educate,

fund research, and find a cure for Kennedy's Disease

Join Today

Together we will make a difference

 Back to Top

 Spinal Bulbar Muscular Atrophy

Current Kennedy's Disease Research

Scientists identify mechanism by which inherited neurological disease causes muscle weakness in men

August 11, 2014 - Scientists show bad androgen receptor impairs body's ability to dispose of damaged cells


Stem cell-derived motor neurons from spinal and bulbar muscular atrophy patients

September 08, 2014 - Highlights:  We characterized stem cells and motor neuron derivatives from patients with SBMA. Variation in the repeat expansion mutation was observed in the cultured cells. Reduced HDAC6 levels were found in the derived motor neurons. Motor neurons from 2 patients with long repeats had increased acetylated α-tubulin.


 Peripheral Androgen Receptor Gene Suppression Rescues Disease in Mouse Models of Spinal and Bulbar Muscular Atrophy

May 08, 2014 - Highlights:  AR-targeted antisense oligonucleotides suppressed gene expression in mice. Subcutaneous delivery suppressed AR gene expression in the periphery but not the CNS. Subcutaneous administration rescued disease in two mouse models of SBMA. Peripherally expressed polyQ AR contributes to disease and is a therapeutic target

Click here to read these articles and more

Back to Top

, X-linked Spinal Bulbar Muscular

 

Atrophy, SBMA, neuromuscular disease, support group